REFLECTIONS ON THE RESPONSIBLE CONDUCT OF CANCER RESEARCH

Reflections on the responsible conduct of cancer research

Abstract Most cancer researchers regularly practice the responsible conduct of research (RCR) without consciously considering it.As professional scientists, google pixel 7 freedom we simply do what we are trained to do.However, as we train a new generation of cancer researchers in our laboratories, we must be vigilant against undue complacency.In a

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Dynamics of HIV-containing compartments in macrophages reveal sequestration of virions and transient surface connections.

During HIV pathogenesis, infected macrophages behave as "viral reservoirs" that accumulate and retain virions within dedicated internal Virus-Containing Compartments (VCCs).The nature of VCCs remains ill characterized and controversial.Using wild-type HIV-1 and a replication-competent HIV-1 carrying GFP internal to the Gag precursor, we analyzed th

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A single cell atlas of frozen shoulder capsule identifies features associated with inflammatory fibrosis resolution

Abstract Frozen shoulder is a spontaneously self-resolving chronic inflammatory fibrotic human disease, which distinguishes the condition from most fibrotic kicker pro comp 10 diseases that are progressive and irreversible.Using single-cell analysis, we identify pro-inflammatory MERTKlowCD48+ macrophages and MERTK + LYVE1 + MRC1+ macrophages enrich

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